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Investigating prebiotic chemistry and the fundamental features of life like metabolism, information, self-reproduction, natural selection and computation, is significant within the origins of life research. In this context, one of the key elements constitutes the synthesis of chemistry-based natural-life-mimicking artificial or synthetic living systems, starting from a homogeneous aqueous blend of a few strictly non-biochemical compounds, using a technique called polymerization-induced self-assembly (PISA). In one of the studies, gradient sequence-controlled polymers were generated through PET-RAFT-PISA

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